Article
Meta-analysis supports GWAS-implicated link between GRM3 and schizophrenia risk.
Translational psychiatry - 8 Aug 2017
Saini S M, Mancuso S G, Mostaid Md S, Liu C, Pantelis C, Everall I P, Bousman C A
Abstract excerpt
Genome-wide association study (GWAS) evidence has identified the metabotropic glutamate receptor 3 (GRM3) gene as a potential harbor for schizophrenia risk variants. However, previous meta-analyses have refuted the association between GRM3 single-nucleotide polymorphisms (SNPs) and schizophrenia risk. To reconcile these conflicting findings, we conducted the largest and most comprehensive meta-analysis of 14 SNPs...
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