Article
HLA-DRB1*04 allele is associated with severe malaria in northern Ghana.
The American journal of tropical medicine and hygiene - 1 Feb 2008
Osafo-Addo Awo D, Koram Kwadwo A, Oduro Abraham R, Wilson Michael, Hodgson Abraham, Rogers William O
Abstract excerpt
Several associations between specific HLA alleles and susceptibility or resistance to Plasmodium falciparum malaria have been previously reported, but no associations have been confirmed in multiple populations. We studied associations between HLA-A, -B, and DRB1 alleles and severe malaria in northern Ghana. We analyzed HLA-DRB1*04 in 4,032 subjects from a severe malaria case-control study, 790 severe malaria...
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