Article
Inducible nitric oxide synthase 2 promoter polymorphism and malaria disease severity in children in Southern Ghana.
PloS one - 1 Jan 2018
Dzodzomenyo Mawuli, Ghansah Anita, Ensaw Nana, Dovie Benjamin, Bimi Langbong, Quansah Reginald, Gyan Ben A, Gyakobo Mawuli, Amoani Benjamin
Abstract excerpt
OBJECTIVE: We assessed the association of mutant allele frequencies of nitric oxide synthase 2 (NOS2) gene at two SNPs (-954 and -1173) with malaria disease severity in children from a malaria endemic area in Southern Ghana. METHOD: Using children recruited at the hospital, assigned into clinical subgroups of uncomplicated and severe malaria and matching with their "healthy control" counterparts, we designed a...
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