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Article

Polymorphisms of the HLA-B and HLA-DRB1 genes in Thai malaria patients.

Japanese journal of infectious diseases - 1 Feb 2005

Hananantachai Hathairad, Patarapotikul Jintana, Ohashi Jun, Naka Izumi, Looareesuwan Sornchai, Tokunaga Katsushi

Abstract excerpt

The high degree of polymorphism of human leukocyte antigen (HLA) genes has been suggested to result from natural selection against susceptibility to a variety of infectious pathogens, including malaria. HLA molecules are considered to play a crucial role in the defense of the host against malarial infection, and different HLA class I and class II alleles have been reported to be associated with reduced...

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PMID: 15728986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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