Article
Fc γ receptor IIIB (FcγRIIIB) polymorphisms are associated with clinical malaria in Ghanaian children.
PloS one - 1 Jan 2012
Adu Bright, Dodoo Daniel, Adukpo Selorme, Hedley Paula L, Arthur Fareed K N, Gerds Thomas A, Larsen Severin O, Christiansen Michael, Theisen Michael
Abstract excerpt
Plasmodium falciparum malaria kills nearly a million people annually. Over 90% of these deaths occur in children under five years of age in sub-Saharan Africa. A neutrophil mediated mechanism, the antibody dependent respiratory burst (ADRB), was recently shown to correlate with protection from clinical malaria. Human neutrophils constitutively express Fc gamma receptor-FcγRIIA and FcγRIIIB by which they interact...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
