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Article

Human leukocyte antigen class I polymorphisms influence the mild clinical manifestation of Plasmodium falciparum infection in Ghanaian children.

Human immunology - 1 Oct 2011

Yamazaki Akiko, Yasunami Michio, Ofori Michael, Horie Hitomi, Kikuchi Mihoko, Helegbe Gideon, Takaki Akiko, Ishii Kazunari, Omar Ahmeddin Hassan, Akanmori Bartholomew D, Hirayama Kenji

Abstract excerpt

A prospective study that included 429 children for active detection of mild malaria was conducted in a coastal region of Ghana to reveal whether the incidence of malaria is affected by human leukocyte antigen (HLA) polymorphism. During 12 months of follow-up, 85 episodes of mild clinical malaria in 74 individuals were observed, and 34 episodes among them were accompanied with significant parasitemia at >5000...

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PMID: 21756958
DOI: 10.1016/j.humimm.2011.06.007

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Source receipt: pubmed, retrieved 7 Sept 2026.

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