Article
IL5RA and TNFRSF6B gene variants are associated with sporadic IgA nephropathy.
Journal of the American Society of Nephrology : JASN - 1 May 2008
Liu Xiao-Qing, Paterson Andrew D, He Ning, St George-Hyslop Peter, Rauta Virpi, Gronhagen-Riska Carola, Laakso Markku, Thibaudin Lise, Berthoux Francois, Cattran Daniel, Pei York
Abstract excerpt
Familial clustering and genome-wide linkage scans strongly support a genetic susceptibility to familial IgA nephropathy (IgAN), but genetic factors that predispose to sporadic IgAN are unknown. A high-throughput single nucleotide polymorphism (SNP) association study was conducted using a customized Illumina BeadChip in 732 white patients with biopsy-proven IgAN and 503 control subjects from Canada, France, and...
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