Article
Genetic polymorphisms in TNFSF13 and FDX1 are associated with IgA nephropathy in the Han Chinese population.
Human immunology - 1 Nov 2015
Niu Dan, Gao Ya, Xie Liyi, Sun Jiping, Lu Wanhong, Jin Gang, Hao Yaning, Zhang Yali, Yin Aiping, Geng Yingzhou, Zhang Wenjing, Chen Cuiping, Li Shengbin
Abstract excerpt
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, and its pathogenesis is influenced by both genetic and environmental factors. In this study, we evaluated 23 tag single-nucleotide polymorphisms (tSNPs) in 21 IgAN-associated genes, in 200 subjects with IgAN and 310 healthy gender- and age-matched unrelated control subjects with no history of renal disease or hypertension. Using the...
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