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Article

The Caenorhabditis elegans PcG-like gene sop-2 regulates the temporal and sexual specificities of cell fates.

Genetics - 1 Mar 2008

Cai Qingchun, Sun Yinyan, Huang Xinxin, Guo Cong, Zhang Yuxia, Zhu Zuoyan, Zhang Hong

Abstract excerpt

How spatial, temporal, and sexual specific cues are integrated to specify distinct cell fates during multicellular organism development is largely unknown. Here we demonstrate that the Caenorhabditis elegans PcG-like gene sop-2 determines the temporal and sexual specificities of a row of hypodermal seam cells, in addition to specifying their positional identities. Loss-of-function of sop-2 causes premature...

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Identifiers

PMID: 18245856
DOI: 10.1534/genetics.108.086678
PMCID: PMC2278068

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