Article
The Paired-box protein PAX-3 regulates the choice between lateral and ventral epidermal cell fates in C. elegans.
Developmental biology - 15 Apr 2016
Thompson Kenneth W, Joshi Pradeep, Dymond Jessica S, Gorrepati Lakshmi, Smith Harold E, Krause Michael W, Eisenmann David M
Abstract excerpt
The development of the single cell layer skin or hypodermis of Caenorhabditis elegans is an excellent model for understanding cell fate specification and differentiation. Early in C. elegans embryogenesis, six rows of hypodermal cells adopt dorsal, lateral or ventral fates that go on to display distinct behaviors during larval life. Several transcription factors are known that function in specifying these major...
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