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Article

The Paired-box protein PAX-3 regulates the choice between lateral and ventral epidermal cell fates in C. elegans.

Developmental biology - 15 Apr 2016

Thompson Kenneth W, Joshi Pradeep, Dymond Jessica S, Gorrepati Lakshmi, Smith Harold E, Krause Michael W, Eisenmann David M

Abstract excerpt

The development of the single cell layer skin or hypodermis of Caenorhabditis elegans is an excellent model for understanding cell fate specification and differentiation. Early in C. elegans embryogenesis, six rows of hypodermal cells adopt dorsal, lateral or ventral fates that go on to display d...

Topics

Animals
Animals, Genetically Modified
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Lineage
Embryo, Nonmammalian
Epidermal Cells
Epidermis
Female
Larva
Luminescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Fluorescence

Mutation

Paired Box Transcription Factors

RNA Interference

Vulva

Source

Open in PubMed Open full text

Identifiers

PMID: 26953187
DOI: 10.1016/j.ydbio.2016.03.002
PMCID: PMC4846358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-26953187-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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