Article
The Caenorhabditis elegans heterochronic gene lin-14 coordinates temporal progression and maturation in the egg-laying system.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2009
Johnson Ryan W, Liu Leah Y, Hanna-Rose Wendy, Chamberlin Helen M
Abstract excerpt
Heterochronic genes function to ensure the timing of stage-specific developmental events in C. elegans. Mutations in these genes cause certain developmental programs to be executed in a precocious or retarded manner. Canonical precocious (loss-of-function) and retarded (gain-of-function) mutations in the lin-14 gene lead to elimination or reiteration of larval stage-specific cellular events. Here, we describe a...
Topics
- Amino Acid Sequence
- Animals
- Body Patterning
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Differentiation
- Female
- Gene Expression Regulation, Developmental
- Larva
- Molecular Sequence Data