Article
Novel heterochronic functions of the Caenorhabditis elegans period-related protein LIN-42.
Developmental biology - 1 Jan 2006
Tennessen Jason M, Gardner Heather F, Volk Mandy L, Rougvie Ann E
Abstract excerpt
LIN-42, the Caenorhabditis elegans homolog of the Period (Per) family of circadian rhythm proteins, functions as a member of the heterochronic pathway, regulating temporal cell identities. We demonstrate that lin-42 acts broadly, timing developmental events in the gonad, vulva, and sex myoblasts, in addition to its well-established role in timing terminal differentiation of the hypodermis. In the vulva, sex...
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