Article
DSH-2 regulates asymmetric cell division in the early C. elegans somatic gonad.
Mechanisms of development - 1 Jun 2005
Chang Weiru, Lloyd Christine E, Zarkower David
Abstract excerpt
Like other organs, the C. elegans gonad develops from a simple primordium that must undergo axial patterning to generate correct adult morphology. Proximal/distal (PD) polarity in the C. elegans gonad is established early during gonadogenesis by the somatic gonad precursor cells, Z1 and Z4. Z1 and Z4 each divide asymmetrically to generate one daughter with a proximal fate and one with a distal fate. PD polarity...
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