Article
RNA-binding proteins SOP-2 and SOR-1 form a novel PcG-like complex in C. elegans.
Development (Cambridge, England) - 1 Mar 2006
Zhang Tingting, Sun Yinyan, Tian E, Deng Hansong, Zhang Yuxia, Luo Xin, Cai Qingchun, Wang Huayi, Chai Jijie, Zhang Hong
Abstract excerpt
We describe the identification and characterization of a novel PcG gene in C. elegans, sor-1, which is involved in global repression of Hox genes. sor-1 encodes a novel protein with an RNA-binding activity. We provide evidence that SOR-1 and the previously identified RNA-binding protein SOP-2 may constitute an RNA-binding complex in Hox gene repression. SOR-1 and SOP-2 directly interact with each other and are...
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