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Article

Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification.

Genetics - 1 Mar 2008

Stylianou Ioannis M, Affourtit Jason P, Shockley Keith R, Wilpan Robert Y, Abdi Fadi A, Bhardwaj Sanjeev, Rollins Jarod, Churchill Gary A, Paigen Beverly

Abstract excerpt

Previous quantitative trait locus (QTL) analysis of an intercross involving the inbred mouse strains NZB/BlNJ and SM/J revealed QTL for a variety of complex traits. Many QTL have large intervals containing hundreds of genes, and methods are needed to rapidly sort through these genes for probable candidates. We chose nine QTL: the three most significant for high-density lipoprotein (HDL) cholesterol, gallstone...

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Identifiers

PMID: 18245842
DOI: 10.1534/genetics.107.081216
PMCID: PMC2278051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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