Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila growth and development in the absence of dMyc and dMnt.

Developmental biology - 15 Mar 2008

Pierce Sarah B, Yost Cynthia, Anderson Sarah A R, Flynn Erin M, Delrow Jeffrey, Eisenman Robert N

Abstract excerpt

Myc oncoproteins are essential regulators of the growth and proliferation of mammalian cells. In Drosophila the single ortholog of Myc (dMyc), encoded by the dm gene, influences organismal size and the growth of both mitotic and endoreplicating cells. A null mutation in dm results in attenuated endoreplication and growth arrest early in larval development. Drosophila also contains a single ortholog of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Genes, Insect

Share to Metamorphosis, Biological

Share to Repressor Proteins

Share to Wings, Animal

Source

Open in PubMed Open full text

Identifiers

PMID: 18241851
DOI: 10.1016/j.ydbio.2007.12.026
PMCID: PMC2322934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila growth and development in the absence of dMyc and dMnt.PMID 18241851Read ↗

The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster.Semantic proximity Read ↗

Max-independent functions of Myc in Drosophila melanogaster.Semantic proximity Read ↗

Drosophila myc regulates cellular growth during development.Semantic proximity Read ↗

The bantam gene regulates Drosophila growth.Semantic proximity Read ↗

Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6.Semantic proximity Read ↗

Myc-regulated miRNAs modulate p53 expression and impact animal survival under nutrient deprivationSemantic proximity Read ↗

Mutations in the Drosophila mitochondrial tRNA amidotransferase, bene/gatA, cause growth defects in mitotic and endoreplicating tissues.Semantic proximity Read ↗

Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.Semantic proximity Read ↗

Drosophila ribosomal protein mutants control tissue growth non-autonomously via effects on the prothoracic gland and ecdysone.Semantic proximity Read ↗

The Drosophila Par domain protein I gene, Pdp1, is a regulator of larval growth, mitosis and endoreplication.Semantic proximity Read ↗

The miRNA machinery targets Mei-P26 and regulates Myc protein levels in the Drosophila wing.Semantic proximity Read ↗

dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.