Article
The Drosophila Par domain protein I gene, Pdp1, is a regulator of larval growth, mitosis and endoreplication.
Developmental biology - 1 Jan 2006
Reddy Karen L, Rovani Margritte K, Wohlwill Arthur, Katzen Alisa, Storti Robert V
Abstract excerpt
PDP1 is a basic leucine zipper (bZip) transcription factor that is expressed at high levels in the muscle, epidermis, gut and fat body of the developing Drosophila embryo. We have identified three mutant alleles of Pdp1, each having a similar phenotype. Here, we describe in detail the Pdp1 mutant allele, Pdp1(p205), which is null for both Pdp1 RNA and protein. Interestingly, homozygous Pdp1(p205) embryos develop...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.