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Article

Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.

Proceedings of the National Academy of Sciences of the United States of America - 16 Aug 2005

Bellosta Paola, Hulf Toby, Balla Diop Soda, Usseglio Fabrice, Pradel Jacques, Aragnol Denise, Gallant Peter

Abstract excerpt

The transcription factor dMyc is the sole Drosophila ortholog of the vertebrate c-myc protooncogenes and a central regulator of growth and cell-cycle progression during normal development. We have investigated the molecular basis of dMyc function by analyzing its interaction with the putative transcriptional cofactors Tip48/Reptin (Rept) and Tip49/Pontin (Pont). We demonstrate that Rept and Pont have conserved...

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Identifiers

PMID: 16087886
DOI: 10.1073/pnas.0408945102
PMCID: PMC1187951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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