Article
The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster.
Molecular and cellular biology - 1 Aug 2005
Loo Lenora W M, Secombe Julie, Little John T, Carlos Leni-Sue, Yost Cynthia, Cheng Pei-Feng, Flynn Erin M, Edgar Bruce A, Eisenman Robert N
Abstract excerpt
The Myc-Max-Mad/Mnt network of transcription factors has been implicated in oncogenesis and the regulation of proliferation in vertebrate cells. The identification of Myc and Max homologs in Drosophila melanogaster has demonstrated a critical role for dMyc in cell growth control. In this report, we identify and characterize the third member of this network, dMnt, the sole fly homolog of the mammalian Mnt and Mad...
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