Article

Myc-regulated miRNAs modulate p53 expression and impact animal survival under nutrient deprivation

2023-03-29

Abstract excerpt

<h4>ABSTRACT</h4> The conserved transcription factor Myc regulates cell growth, proliferation and apoptosis, and its deregulation has been associated with human pathologies. Although specific miRNAs have been identified as fundamental components of the Myc tumorigenic program, how Myc regulates miRNA biogenesis remains controversial. Here we showed that Myc functions as an important regulator of miRNA biogenesis...

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Literature Corpus work: 9a4099ae-293f-5243-ac14-3062aabe4dda
DOI: 10.1101/2023.03.28.534500

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