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Article

Association between the paraoxonase-1 192Q>R allelic variant and coronary endothelial dysfunction in patients with early coronary artery disease.

Mayo Clinic proceedings - 1 Feb 2008

Lavi Shahar, McConnell Joseph P, Lavi Ronit, Barsness Gregory W, Rihal Charanjit S, Novak Gregory D, Lerman Lilach O, Lerman Amir

Abstract excerpt

OBJECTIVE: To test the hypothesis that allelic variants of the paraoxonase-1 gene are associated with endothelial dysfunction, an early stage of atherosclerosis. PATIENTS AND METHODS: We assessed 192Q>R and 55L>M allelic variants of the paraoxonase gene and coronary endothelial function in response to intracoronary acetylcholine in 99 patients (52 with homozygous QQ, 47 with homozygous RR or heterozygous QR). The...

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Identifiers

PMID: 18241625
DOI: 10.4065/83.2.158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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