Article
Paraoxonase 1 gene polymorphisms contribute to coronary artery disease risk among north Indians.
Indian journal of medical sciences - 1 Aug 2009
Agrawal S, Tripathi Gaurav, Prajnya R, Sinha Nakul, Gilmour A, Bush L, Mastana S
Abstract excerpt
BACKGROUND: Polymorphisms in paraoxonase 1 (PON1) coding for PON1 enzyme have been studied as genetic markers of coronary artery disease (CAD). PON1 Q192R and PON1 L55M polymorphisms have been analyzed extensively, but data on association and role of these polymorphisms in the etiology of CAD are conflicting. In this study, we tested the genetic association between PON1 Q192R and PON1 L55M polymorphisms and CAD...
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