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Article

The association of paraoxonase 1 gene L55M polymorphism with the extent and severity of coronary artery disease in the Turkish population and its dependence on gender.

Anatolian journal of cardiology - 1 Mar 2016

Sayın Kocakap Derya Beyza, Doğru Mehmet Tolga, Şimşek Vedat, Çabuk Feryal, Yıldırım Nesligül, Çelik Yunus, Alyılmaz Bekmez Sibel, Erdem Solmaz

Abstract excerpt

OBJECTIVE: Coronary artery disease (CAD) is a common, complex, and progressive disorder characterized by the accumulation of lipids and fibrous elements in the arteries. It is one of the leading causes of death in industrialized nations. Oxidative modification of low-density lipoprotein (LDL) in the arterial wall plays an important role in the initiation and progression of atherosclerosis. Paraoxonase1 (PON1) is...

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Aryldialkylphosphatase
Coronary Artery Disease
Electrocardiography
Risk Factors
Severity of Illness Index

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PMID: 26467378
DOI: 10.5152/akd.2015.6010
PMCID: PMC5336803

Genes

PON1
CAD

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