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Article

Choline metabolism and risk of breast cancer in a population-based study.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2008

Xu Xinran, Gammon Marilie D, Zeisel Steven H, Lee Yin Leng, Wetmur James G, Teitelbaum Susan L, Bradshaw Patrick T, Neugut Alfred I, Santella Regina M, Chen Jia

Abstract excerpt

Choline is an essential nutrient required for methyl group metabolism, but its role in carcinogenesis and tumor progression is not well understood. By utilizing a population-based study of 1508 cases and 1556 controls, we investigated the associations of dietary intake of choline and two related micronutrients, methionine and betaine, and risk of breast cancer. The highest quintile of choline consumption was...

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Identifiers

PMID: 18230680
DOI: 10.1096/fj.07-101279
PMCID: PMC2430758

Genes

PEMT
CHDH
BHMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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