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Article

Dietary choline and betaine intake, choline-metabolising genetic polymorphisms and breast cancer risk: a case-control study in China.

The British journal of nutrition - 1 Sept 2016

Du Yu-Feng, Luo Wei-Ping, Lin Fang-Yu, Lian Zhen-Qiang, Mo Xiong-Fei, Yan Bo, Xu Ming, Huang Wu-Qing, Huang Jing, Zhang Cai-Xia

Abstract excerpt

Choline and betaine are essential nutrients involved in one-carbon metabolism and have been hypothesised to affect breast cancer risk. Functional polymorphisms in genes encoding choline-related one-carbon metabolism enzymes, including phosphatidylethanolamine N-methyltransferase (PEMT), choline dehydrogenase (CHDH) and betaine-homocysteine methyltransferase (BHMT), have important roles in choline metabolism and...

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Source

Identifiers

PMID: 27488260
DOI: 10.1017/S0007114516002956

Genes

BHMT
PEMT
CHDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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