Article
Associations between Plasma Choline Metabolites and Genetic Polymorphisms in One-Carbon Metabolism in Postmenopausal Women: The Women's Health Initiative Observational Study.
The Journal of nutrition - 19 Nov 2020
Ilozumba Mmadili N, Cheng Ting-Yuan D, Neuhouser Marian L, Miller Joshua W, Beresford Shirley A A, Duggan David J, Toriola Adetunji T, Song Xiaoling, Zheng Yingye, Bailey Lynn B, Shadyab Aladdin H, Liu Simin, Malysheva Olga, Caudill Marie A, Ulrich Cornelia M
Abstract excerpt
BACKGROUND: Choline plays an integral role in one-carbon metabolism in the body, but it is unclear whether genetic polymorphisms are associated with variations in plasma choline and its metabolites. OBJECTIVES: This study aimed to evaluate the association of genetic variants in choline and one-carbon metabolism with plasma choline and its metabolites. METHODS: We analyzed data from 1423 postmenopausal women in a...
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