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Article

Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma.

The American journal of clinical nutrition - 1 Aug 2010

Fischer Leslie M, da Costa Kerry Ann, Galanko Joseph, Sha Wei, Stephenson Brigitte, Vick Julie, Zeisel Steven H

Abstract excerpt

BACKGROUND: Choline is essential for infant nutrition, and breast milk is a rich source of this nutrient. Common single nucleotide polymorphisms (SNPs) change dietary requirements for choline intake. OBJECTIVE: The aim of this study was to determine whether total choline intake and/or SNPs influence concentrations of choline and its metabolites in human breast milk and plasma. DESIGN: We gave a total of 103...

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Identifiers

PMID: 20534746
DOI: 10.3945/ajcn.2010.29459
PMCID: PMC2904035

Genes

MTHFR
PEMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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