Article
A genome screen of a large bipolar affective disorder pedigree supports evidence for a susceptibility locus on chromosome 13q.
Molecular psychiatry - 1 Jul 2001
Badenhop R F, Moses M J, Scimone A, Mitchell P B, Ewen K R, Rosso A, Donald J A, Adams L J, Schofield P R
Abstract excerpt
Bipolar affective disorder is a severe mood disorder that afflicts approximately 1% of the population worldwide. Twin and adoption studies have indicated that genetic factors contribute to the disorder and while many chromosomal regions have been implicated, no susceptibility genes have been identified. In this present study, we undertook a 10 cM genome screen using 400 microsatellite markers in a large...
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