Article
A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish.
Nature genetics - 1 Apr 1996
Ginns E I, Ott J, Egeland J A, Allen C R, Fann C S, Pauls D L, Weissenbachoff J, Carulli J P, Falls K M, Keith T P, Paul S M
Abstract excerpt
The most characteristic features of bipolar affective disorder (manic-depressive illness) are episodes of mania (bipolar I, BPI) or hypomania (bipolar II, BPII) interspersed with periods of depression. Manic-depressive illness afflicts about one percent of the population, and if untreated, is ass...
Topics
- Alleles
- Bipolar Disorder
- Chromosome Mapping
- Chromosomes, Human, Pair 13
- Chromosomes, Human, Pair 15
- Chromosomes, Human, Pair 6
- Ethnicity
- Female
- Genetic Linkage
- Genetic Markers
- Genome, Human
- Humans
- Lod Score
- Male
- Models, Genetic
- Pedigree