Article
A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q.
Human molecular genetics - 1 Dec 2001
Cichon S, Schumacher J, Müller D J, Hürter M, Windemuth C, Strauch K, Hemmer S, Schulze T G, Schmidt-Wolf G, Albus M, Borrmann-Hassenbach M, Franzek E, Lanczik M, Fritze J, Kreiner R, Reuner U, Weigelt B, Minges J, Lichtermann D, Lerer B, Kanyas K, Baur M P, Wienker T F, Maier W, Rietschel M, Propping P, Nöthen M M
Abstract excerpt
Bipolar affective disorder (BPAD), also known as manic depressive illness, is a severe psychiatric disorder characterized by episodes of mania and depression. It has a lifetime prevalence of approximately 1% in all human populations. In order to identify chromosomal regions containing genes that play a role in determining susceptibility to this psychiatric condition, we have conducted a complete genome screen...
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