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Article

A susceptibility locus for bipolar affective disorder on chromosome 4q35.

American journal of human genetics - 1 May 1998

Adams L J, Mitchell P B, Fielder S L, Rosso A, Donald J A, Schofield P R

Abstract excerpt

Bipolar affective disorder (BAD) affects approximately 1% of the population and shows strong heritability. To identify potential BAD susceptibility loci, we undertook a 15-cM genome screen, using 214 microsatellite markers on the 35 most informative individuals of a large, statistically powerful pedigree. Data were analyzed by parametric two-point linkage methods under several diagnostic models. LOD scores >1.00...

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Source

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Identifiers

PMID: 9545396
DOI: 10.1086/301826
PMCID: PMC1377083

Genes

BAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A susceptibility locus for bipolar affective disorder on chromosome 4q35.PMID 9545396Read ↗

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A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

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