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Article

A pharmacogenetic study of pregnane X receptor (NR1I2) in Han Chinese.

Current drug metabolism - 1 Dec 2007

Wang Xue-Ding, Li Jia-Li, Su Qi-Biao, Deng Xiao-Ying, Lu Yan, Chen Jie, Zhang Jin-Xin, Zhao Li-Zi, Zuo Zhong, Chan Eli, Chen Xiao, Chowbay Balram, Xue Charlie Changli, Huang Min, Zhou Shu-Feng

Abstract excerpt

The pregnane X receptor (PXR/NR1I2) gene is a critical transcriptional regulator of a number of important drug metabolizing enzymes and transporters. This study was undertaken to determine the frequencies of single nucleotide polymorphisms (SNPs) and haplotypes and to detect yet unknown SNPs in the NR1I2 gene in 210 unrelated healthy Han Chinese in comparison with other ethnic groups. We also characterized the...

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PMID: 18220558
DOI: 10.2174/138920007782798199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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