Article
Tetrahymena IFT122A is not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body.
Journal of cell science - 15 Feb 2008
Tsao Che-Chia, Gorovsky Martin A
Abstract excerpt
Intraflagellar transport (IFT) moves multiple protein particles composed of two biochemically distinct complexes, IFT-A and IFT-B, bi-directionally within cilia and is essential for cilia assembly and maintenance. We identified an ORF from the Tetrahymena macronuclear genome sequence, encoding IFT122A, an ortholog of an IFT-A complex protein. Tetrahymena IFT122A is induced during cilia regeneration, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
