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Article

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.

eLife - 1 Jan 2014

Ishikawa Hiroaki, Ide Takahiro, Yagi Toshiki, Jiang Xue, Hirono Masafumi, Sasaki Hiroyuki, Yanagisawa Haruaki, Wemmer Kimberly A, Stainier Didier Yr, Qin Hongmin, Kamiya Ritsu, Marshall Wallace F

Abstract excerpt

Cilia/flagella are assembled and maintained by the process of intraflagellar transport (IFT), a highly conserved mechanism involving more than 20 IFT proteins. However, the functions of individual IFT proteins are mostly unclear. To help address this issue, we focused on a putative IFT protein TTC26/DYF13. Using live imaging and biochemical approaches we show that TTC26/DYF13 is an IFT complex B protein in...

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Algal Proteins
Chlamydomonas reinhardtii
Cilia
Embryo, Nonmammalian
Flagella

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Knockdown Techniques

Zebrafish Proteins

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PMID: 24596149
DOI: 10.7554/eLife.01566
PMCID: PMC3936282

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Click a neighbor to travelStep 1 · 12 closest

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.PMID 24596149Read ↗

An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes.Semantic proximity Read ↗

Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a component of the intraflagellar transport machinery in sensory cilia.Semantic proximity Read ↗

Sensory ciliogenesis in Caenorhabditis elegans: assignment of IFT components into distinct modules based on transport and phenotypic profiles.Semantic proximity Read ↗

Functional genomics of intraflagellar transport-associated proteins in C. elegans.Semantic proximity Read ↗

The WD repeat-containing protein IFTA-1 is required for retrograde intraflagellar transport.Semantic proximity Read ↗

Caenorhabditis elegans DYF-11, an orthologue of mammalian Traf3ip1/MIP-T3, is required for sensory cilia formation.Semantic proximity Read ↗

Tetrahymena IFT122A is not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body.Semantic proximity Read ↗

Role for the IFT-A Complex in Selective Transport to the Primary Cilium.Semantic proximity Read ↗

Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motorsSemantic proximity Read ↗

Architecture of the IFT ciliary trafficking machinery and interplay between its componentsSemantic proximity Read ↗

IFT57 stabilizes the assembled intraflagellar transport complex and mediates transport of motility-related flagellar cargo.Semantic proximity Read ↗

Review: Intraflagellar transport proteins in the retina.Semantic proximity Read ↗

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