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Article

Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes.

Molecular biology of the cell - 1 Mar 2008

Absalon Sabrina, Blisnick Thierry, Kohl Linda, Toutirais Géraldine, Doré Gwénola, Julkowska Daria, Tavenet Arounie, Bastin Philippe

Abstract excerpt

Intraflagellar transport (IFT) is the bidirectional movement of protein complexes required for cilia and flagella formation. We investigated IFT by analyzing nine conventional IFT genes and five novel putative IFT genes (PIFT) in Trypanosoma brucei that maintain its existing flagellum while assem...

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Source

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Identifiers

PMID: 18094047
DOI: 10.1091/mbc.e07-08-0749
PMCID: PMC2262991

Genes

IFT52
IFT20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18094047-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes.PMID 18094047Read ↗

Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length.Semantic proximity Read ↗

Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella.Semantic proximity Read ↗

Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagellar membrane formationSemantic proximity Read ↗

FAP20 is required for flagellum assembly in <i>Trypanosoma brucei</i>Semantic proximity Read ↗

IFT25 is required for the construction of the trypanosome flagellumSemantic proximity Read ↗

Tetrahymena IFT122A is not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body.Semantic proximity Read ↗

A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum.Semantic proximity Read ↗

Assembly of the flagellum and its role in cell morphogenesis in Trypanosoma bruceiSemantic proximity Read ↗

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