Article
Tetrahymena RIB72A and RIB72B are microtubule inner proteins in the ciliary doublet microtubules.
Molecular biology of the cell - 15 Oct 2018
Stoddard Daniel, Zhao Ying, Bayless Brian A, Gui Long, Louka Panagiota, Dave Drashti, Suryawanshi Swati, Tomasi Raphaël F-X, Dupuis-Williams Pascale, Baroud Charles N, Gaertig Jacek, Winey Mark, Nicastro Daniela
Abstract excerpt
Doublet and triplet microtubules are essential and highly stable core structures of centrioles, basal bodies, cilia, and flagella. In contrast to dynamic cytoplasmic micro-tubules, their luminal surface is coated with regularly arranged microtubule inner proteins (MIPs). However, the protein composition and biological function(s) of MIPs remain poorly understood. Using genetic, biochemical, and imaging...
Topics
- Axoneme
- Cilia
- Fluorescence
- Gene Knockout Techniques
- Green Fluorescent Proteins
- Microtubule Proteins
- Microtubules
- Models, Biological
- Mutation
- Phagocytosis