Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypoxia regulates assembly of cilia in suppressors of Tetrahymena lacking an intraflagellar transport subunit gene.

Molecular biology of the cell - 1 Aug 2003

Brown Jason M, Fine Noah A, Pandiyan Gautham, Thazhath Rupal, Gaertig Jacek

Abstract excerpt

We cloned a Tetrahymena thermophila gene, IFT52, encoding a homolog of the Chlamydomonas intraflagellar transport protein, IFT52. Disruption of IFT52 led to loss of cilia and incomplete cytokinesis, a phenotype indistinguishable from that of mutants lacking kinesin-II, a known ciliary assembly tr...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algal Proteins
Share to Cell Count
Share to Cell Hypoxia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kinesins

Share to Protozoan Proteins

Share to Sequence Homology

Share to Tetrahymena thermophila

Source

Open in PubMed Open full text

Identifiers

PMID: 12925756
DOI: 10.1091/mbc.e03-03-0166
PMCID: PMC181560

Genes

IFT52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12925756-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypoxia regulates assembly of cilia in suppressors of Tetrahymena lacking an intraflagellar transport subunit gene.PMID 12925756Read ↗

Tetrahymena IFT122A is not essential for cilia assembly but plays a role in returning IFT proteins from the ciliary tip to the cell body.Semantic proximity Read ↗

Kinesin-II is preferentially targeted to assembling cilia and is required for ciliogenesis and normal cytokinesis in Tetrahymena.Semantic proximity Read ↗

The emerging functions of intraflagellar transport 52 in ciliary transport and ciliopathies.Semantic proximity Read ↗

IFT57 stabilizes the assembled intraflagellar transport complex and mediates transport of motility-related flagellar cargo.Semantic proximity Read ↗

Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis.Semantic proximity Read ↗

Distinct mutants of retrograde intraflagellar transport (IFT) share similar morphological and molecular defects.Semantic proximity Read ↗

Manipulating ciliary protein-encoding genes in Tetrahymena thermophila.Semantic proximity Read ↗

Dynein-2 and ciliogenesis in Tetrahymena.Semantic proximity Read ↗

Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin.Semantic proximity Read ↗

Dynein-2 affects the regulation of ciliary length but is not required for ciliogenesis in Tetrahymena thermophila.Semantic proximity Read ↗

Assembly of IFT trains at the ciliary base depends on IFT74.Semantic proximity Read ↗

Intraflagellar transport (IFT) protein IFT25 is a phosphoprotein component of IFT complex B and physically interacts with IFT27 in Chlamydomonas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.