Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements.

European journal of clinical pharmacology - 1 May 2008

Gaedigk Andrea, Coetsee Christa

Abstract excerpt

OBJECTIVE: The highly polymorphic CYP2D6 gene locus has been extensively scrutinised in the major ethnic populations, but little is known about the locus for many indigenous and unique admixed populations, including the Coloureds of South Africa. This study aimed at characterising the CYP2D6 gene locus in Coloured subjects and predict their phenotype status. METHODS: CYP2D6 genotyping was performed on 99 Coloured...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black People
Share to Cytochrome P-450 CYP2D6
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Phenotype

Share to Polymerase Chain Reaction

Share to South Africa

Share to White People

Source

Identifiers

PMID: 18202841
DOI: 10.1007/s00228-007-0445-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements.PMID 18202841Read ↗

CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants.Semantic proximity Read ↗

Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoplesSemantic proximity Read ↗

Interethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations.Semantic proximity Read ↗

Allelic diversity of the pharmacogene <i>CYP2D6</i> in New Zealand Māori and Pacific peoplesSemantic proximity Read ↗

Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants.Semantic proximity Read ↗

Characterization of CYP2D6 Pharmacogenetic Variation in Sub-Saharan African Populations.Semantic proximity Read ↗

Prediction of CYP2D6 phenotype from genotype across world populations.Semantic proximity Read ↗

Distribution of CYP2D6 alleles and phenotypes in the Brazilian population.Semantic proximity Read ↗

Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution.Semantic proximity Read ↗

Identification of a novel non-functional CYP2D6 allele, CYP2D6*69, in a Caucasian poor metabolizer individual.Semantic proximity Read ↗

Rapid detection of common cytochrome P450 2D6 alleles in Caucasians.Semantic proximity Read ↗

CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.