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Article

Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants.

Pharmacogenomics - 1 Feb 2013

Montané Jaime Lazara Karelia, Lalla Anthony, Steimer Werner, Gaedigk Andrea

Abstract excerpt

BACKGROUND: The highly polymorphic CYP2D6 gene has extensively been studied in many populations, but there is a void of knowledge regarding CYP2D6 pharmacogenetics and activity in populations with unique ancestries and admixture, such as those residing in Trinidad and Tobago. MATERIALS & METHODS: 167 healthy Indo- and 103 Afro-Trinidadians were phenotyped with dextromethorphan and extensively genotyped. Gene...

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PMID: 23394389
DOI: 10.2217/pgs.12.207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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