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Article

CYP2D6 phenotyping with dextromethorphan.

Pharmacological reports : PR - 1 Jan 2000

Wojtczak Anna, Rychlik-Sych Mariola, Krochmalska-Ulacha Eliza, Skretkowicz Jadwiga

Abstract excerpt

Genetically determined individual differences in the ability to oxidize certain drugs have raised recently a considerable interest because of clinical importance of this problem. Determination of CYP2D6 oxidation phenotype is used to obtain more efficient pharmacotherapy and to explain lower efficacy of some drugs and presentation of adverse effects in particular patients. The aim of this study was to identify...

Topics

Administration, Oral
Adolescent
Adult
Aged
Aged, 80 and over
Chromatography, High Pressure Liquid
Cytochrome P-450 CYP2D6
Dextromethorphan
Dextrorphan
Female
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Phenotype

Polymorphism, Genetic

Source

Identifiers

PMID: 18195464

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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