Article
Oxidative phenotype status in related subjects.
Acta poloniae pharmaceutica - 1 Jan 2000
Rychlik-Sych Mariola, Łyczba Magdalena, Skretkowicz Jadwiga
Abstract excerpt
Human population varies with regard to the rate of drug metabolism. Differences in pharmacological activity of a drug in patients who belong to the same population result from a different enzymatic activity and different genotypes of those subjects. The aim of the study was to assess the incidence of extensive (EM) and poor (PM) oxidative phenotypes in related persons and to establish whether any associations...
Topics
- Adolescent
- Adult
- Aged
- Chromatography, High Pressure Liquid
- Dextromethorphan
- Dextrorphan
- Family
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Mothers
- Nuclear Family
- Oxidation-Reduction
- Phenotype
- Polymorphism, Genetic
- Prevalence
