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Article

Analysis of pharmacokinetic parameters for assessment of dextromethorphan metabolic phenotypes.

Journal of biomedical science - 1 Jan 2000

Yeh Geng-Chang, Tao Pao-Luh, Ho Hsiu-O, Lee Yung-Jin, Chen Julia Yi-Ru, Sheu Ming-Thau

Abstract excerpt

In this study, the metabolic ratios of dextromethorphan to dextrorphan (DM/DX) in plasma were calculated at steady state after administering 2 dosage forms (Medicon) and Detusiv) of DM with different release rates. The urinary metabolic ratio for each subject was also determined based on the total drug concentration in the urine. An analysis of pharmacokinetic parameters for determining the DM metabolic phenotype...

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Identifiers

PMID: 12928596
DOI: 10.1007/BF02256117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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