Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of cytochrome P450 2D6 phenotyping in healthy adult Western Indians.

Indian journal of pharmacology - 1 Jan 2000

Gogtay Nithya J, Mali Nitin B, Iyer Krishna, Kadam Prashant P, Sridharan Kannan, Shrimal Divya, Thatte Urmila M

Abstract excerpt

BACKGROUND: Cytochrome P450 2D6 (CYP2D6) metabolizes around 25% of the drugs used in therapeutics and different polymorphisms have been identified in various populations. This study aimed at finding the prevalence of CYP2D6 polymorphisms using dextromethorphan as a probe drug. MATERIALS AND METHODS: Healthy participants were administered 60 mg dextromethorphan after an overnight fast and 5 ml of blood was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dextromethorphan

Share to Phenotype

Share to Polymorphism, Genetic

Share to White People

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 24987171
DOI: 10.4103/0253-7613.132154
PMCID: PMC4071701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of cytochrome P450 2D6 phenotyping in healthy adult Western Indians.PMID 24987171Read ↗

Cytochrome P450 2D6 polymorphism in eastern Indian population.Semantic proximity Read ↗

Genetic polymorphism of CYP2D6 in North Indian subjects.Semantic proximity Read ↗

Genetic polymorphism of CYP2D6 in Karnataka and Andhra Pradesh population in India.Semantic proximity Read ↗

CYP2D6 genotype and phenotype relationship in South Indians.Semantic proximity Read ↗

CYP2D6 genotype and phenotyping by determination of dextromethorphan and metabolites in serum of healthy controls and of patients under psychotropic medication.Semantic proximity Read ↗

Evaluation of CYP2D6 phenotype in the Yoruba Nigerian population.Semantic proximity Read ↗

Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan.Semantic proximity Read ↗

Evaluation of cytochrome P450 2C9 activity in normal, healthy, adult Western Indian population by both phenotyping and genotyping.Semantic proximity Read ↗

In vivo characterization of CYP2D6*12, *29 and *84 using dextromethorphan as a probe drug: a case report.Semantic proximity Read ↗

CYP2D6 phenotyping with dextromethorphan.Semantic proximity Read ↗

Psychiatric Disorder or Adverse Drug Reaction? - How CYP2D6 Metabolizing Activity Can Result in Dextromethorphan Intoxication.Semantic proximity Read ↗

Effects of age and gender on the cytochrome P450 2D6 activity in a Korean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.