Article
Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population.
Malaria journal - 14 Jan 2008
Sinha Swapnil, Mishra Shrawan K, Sharma Shweta, Patibandla Phani K, Mallick Prashant K, Sharma Surya K, Mohanty Sanjib, Pati Sudhanshu S, Mishra Saroj K, Ramteke Bheshaj K, Bhatt Rm, Joshi Hema, Dash Aditya P, Ahuja Ramesh C, Awasthi Shally, Venkatesh Vimala, Habib Saman
Abstract excerpt
BACKGROUND: Susceptibility/resistance to Plasmodium falciparum malaria has been correlated with polymorphisms in more than 30 human genes with most association analyses having been carried out on patients from Africa and south-east Asia. The aim of this study was to examine the possible contribution of genetic variants in the TNF and FCGR2A genes in determining severity/resistance to P. falciparum malaria in...
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