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Article

Tumor necrosis factor-α (TNF-α) -308G >a promoter polymorphism (rs1800629) promotes Asians in susceptibility to Plasmodium falciparum severe malaria: A meta-analysis.

PLoS neglected tropical diseases - 1 Nov 2023

Kongjam Panida, Pabalan Noel, Tharabenjasin Phuntila, Jarjanazi Hamdi, Chaijaroenkul Wanna, Na-Bangchang Kesara

Abstract excerpt

The multifactorial pathogenesis of severe malaria is partly attributed to host genes, such as those encoding cytokines involved in complex inflammatory reactions, namely tumor necrosis factor-alpha (TNF-α). However, the relationship between TNF-α -308G >A gene polymorphism (rs1800629) and the severity of Plasmodium falciparum (P. falciparum) malaria remains unclear, which prompts a meta-analysis to obtain more...

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PMID: 37910577
DOI: 10.1371/journal.pntd.0011735
PMCID: PMC10655976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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