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Article

Mapping of protein-protein interaction sites by the 'absence of interference' approach.

Journal of molecular biology - 29 Feb 2008

Dhayalan Arunkumar, Jurkowski Tomasz P, Laser Heike, Reinhardt Richard, Jia Da, Cheng Xiaodong, Jeltsch Albert

Abstract excerpt

Protein-protein interactions are critical to most biological processes, and locating protein-protein interfaces on protein structures is an important task in molecular biology. We developed a new experimental strategy called the 'absence of interference' approach to determine surface residues involved in protein-protein interaction of established yeast two-hybrid pairs of interacting proteins. One of the proteins...

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Identifiers

PMID: 18191145
DOI: 10.1016/j.jmb.2007.12.032
PMCID: PMC2602804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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