Article
Global analysis of functional surfaces of core histones with comprehensive point mutants.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2007
Matsubara Kazuko, Sano Norihiko, Umehara Takashi, Horikoshi Masami
Abstract excerpt
The core histones are essential components of the nucleosome that act as global negative regulators of DNA-mediated reactions including transcription, DNA replication and DNA repair. Modified residues in the N-terminal tails are well characterized in transcription, but not in DNA replication and DNA repair. In addition, roles of residues in the core globular domains are not yet well characterized in any...
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