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Article

Possible association of ACE gene I/D polymorphism with blood pressure--lowering response to hydrochlorothiazide.

Biomedical and environmental sciences : BES - 1 Oct 2007

Zhou Yong, Wu Shou-Ling, Liu Jian-Qing, Liang Wan-Nian, Liu Gai-Fen

Abstract excerpt

OBJECTIVE: To explore the association between polymorphism in the ACE I/D gene and blood pressure-lowering response to hydrochlorothiazide (HCTZ) in 829 patients. METHODS: HCTZ 12.5 mg was taken once a day for six weeks. The blood pressure reduction and ratio reaching target blood pressure were compared in different ACE genotype groups. RESULTS: The reduction in SBP of patients carrying DD was greater than that...

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Identifiers

PMID: 18188985

Genes

ACE
DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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