Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gender-specific association between ACE gene I/D polymorphism and blood pressure response to hydrochlorothiazide in Han Chinese hypertensive patients.

Biochemical genetics - 1 Dec 2011

Li Yun, Yang Peng, Wu Shouling, Yuan Juxiang, Shen Chong, Wu Ying, Zhao Dandan, Ren Qi, Feng Fumin, Guan Weijun

Abstract excerpt

To evaluate the interaction between the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and gender with individual blood pressure response to hydrochlorothiazide (HCTZ) in hypertensives, we enrolled 829 mild-moderate hypertensive patients. All subjects were given HCTZ (12.5 mg) orally each day for 6 weeks. A total of 776 patients completed the study. There was statistically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antihypertensive Agents
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Gene Frequency

Share to Hydrochlorothiazide

Share to Hypertension

Share to Peptidyl-Dipeptidase A

Share to Sex Factors

Source

Identifiers

PMID: 21647824
DOI: 10.1007/s10528-011-9444-6

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gender-specific association between ACE gene I/D polymorphism and blood pressure response to hydrochlorothiazide in Han Chinese hypertensive patients.PMID 21647824Read ↗

Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide.Semantic proximity Read ↗

Possible association of ACE gene I/D polymorphism with blood pressure--lowering response to hydrochlorothiazide.Semantic proximity Read ↗

Interaction of ACE and CYP11B2 genes on blood pressure response to hydrochlorothiazide in Han Chinese hypertensive patients.Semantic proximity Read ↗

Effects of ACE and ADD1 gene polymorphisms on blood pressure response to hydrochlorothiazide: a meta-analysis.Semantic proximity Read ↗

[Association of polymorphisms in ACE and CYP11B2 genes with antihypertensive effects of hydrochlorothiazide].Semantic proximity Read ↗

Age- and gender-dependent association of the angiotensin-converting enzyme gene with essential hypertension in a Chinese population.Semantic proximity Read ↗

ACE and alpha-adducin polymorphism as markers of individual response to diuretic therapy.Semantic proximity Read ↗

Effect of renin-angiotensin-aldosterone system gene polymorphisms on blood pressure response to antihypertensive treatment.Semantic proximity Read ↗

Relationship between the response to the angiotensin converting enzyme inhibitor imidapril and the angiotensin converting enzyme genotype.Semantic proximity Read ↗

Relation between the angiotensin-converting enzyme insertion/deletion polymorphism and blood pressure in Japanese male subjects.Semantic proximity Read ↗

Angiotensin-converting enzyme gene I/D genotype affected metoprolol-induced reduction in 24-hour average heart rate.Semantic proximity Read ↗

D919G polymorphism of methionine synthase gene is associated with blood pressure response to benazepril in Chinese hypertensive patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.