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Article

Genetic variation in renin predicts the effects of thiazide diuretics.

European journal of clinical investigation - 1 Aug 2011

Huang Chin-Chou, Chung Chia-Min, Hung Shuen-Iu, Leu Hsin-Bang, Wu Tao-Cheng, Huang Po-Hsun, Lin Shing-Jong, Pan Wen-Harn, Chen Jaw-Wen

Abstract excerpt

BACKGROUND: While genetic variants of renin-angiotensin-aldosterone system (RAAS) may modify the blood pressure (BP) response to thiazide diuretics, there was no evidence of genetic variations in renin (REN) playing a role. This study aimed to address the potential effects of genetic variations of RAAS on the response to initial treatment of hydrochlorothiazide (HCTZ). MATERIALS AND METHODS: We enrolled...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21261619
DOI: 10.1111/j.1365-2362.2011.02472.x

Genes

REN
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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